Posaconazole.json

{
  "Version": 79,
  "ExpressionProfiles": [
    {
      "Type": "Transporter",
      "Species": "Human",
      "Molecule": "ABCB1",
      "Category": "Healthy",
      "Parameters": [
        {
          "Path": "ABCB1|Reference concentration",
          "Value": 1.41,
          "Unit": "µmol/l"
        },
        {
          "Path": "ABCB1|Relative expression in blood cells",
          "Value": 0.1065804935
        },
        {
          "Path": "ABCB1|t1/2 (intestine)",
          "Value": 1380.0,
          "Unit": "min"
        },
        {
          "Path": "ABCB1|t1/2 (liver)",
          "Value": 2160.0,
          "Unit": "min"
        },
        {
          "Path": "Organism|Bone|Intracellular|ABCB1|Relative expression",
          "Value": 0.0341950646
        },
        {
          "Path": "Organism|Brain|Intracellular|ABCB1|Relative expression",
          "Value": 0.1072855464
        },
        {
          "Path": "Organism|Gonads|Intracellular|ABCB1|Relative expression",
          "Value": 0.024559342
        },
        {
          "Path": "Organism|Heart|Intracellular|ABCB1|Relative expression",
          "Value": 0.059106933
        },
        {
          "Path": "Organism|Kidney|Intracellular|ABCB1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|ABCB1|Relative expression",
          "Value": 0.1562867215
        },
        {
          "Path": "Organism|LargeIntestine|Mucosa|ColonAscendens|Intracellular|ABCB1|Relative expression",
          "Value": 0.1562867215
        },
        {
          "Path": "Organism|LargeIntestine|Mucosa|ColonDescendens|Intracellular|ABCB1|Relative expression",
          "Value": 0.1562867215
        },
        {
          "Path": "Organism|LargeIntestine|Mucosa|ColonSigmoid|Intracellular|ABCB1|Relative expression",
          "Value": 0.1562867215
        },
        {
          "Path": "Organism|LargeIntestine|Mucosa|ColonTransversum|Intracellular|ABCB1|Relative expression",
          "Value": 0.1562867215
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|ABCB1|Relative expression",
          "Value": 0.2702702703
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|ABCB1|Relative expression",
          "Value": 0.2702702703
        },
        {
          "Path": "Organism|Lung|Intracellular|ABCB1|Relative expression",
          "Value": 0.0927144536
        },
        {
          "Path": "Organism|Muscle|Intracellular|ABCB1|Relative expression",
          "Value": 0.0180963572
        },
        {
          "Path": "Organism|Pancreas|Intracellular|ABCB1|Relative expression",
          "Value": 0.0200940071
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|ABCB1|Relative expression",
          "Value": 0.3960047004
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|ABCB1|Relative expression",
          "Value": 0.3960047004
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|ABCB1|Relative expression",
          "Value": 0.3960047004
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|ABCB1|Relative expression",
          "Value": 0.3960047004
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|ABCB1|Relative expression",
          "Value": 0.3960047004
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|ABCB1|Relative expression",
          "Value": 0.3960047004
        },
        {
          "Path": "Organism|Spleen|Intracellular|ABCB1|Relative expression",
          "Value": 0.1047003525
        },
        {
          "Path": "Organism|Stomach|Intracellular|ABCB1|Relative expression",
          "Value": 0.0367802585
        }
      ],
      "TransportType": "Efflux",
      "Expression": [
        {
          "Name": "Bone",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Brain",
          "TransportDirection": "EffluxBrainInterstitialToPlasma",
          "CompartmentName": "Plasma"
        },
        {
          "Name": "Brain",
          "TransportDirection": "EffluxBrainTissueToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "Fat",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Gonads",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Heart",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Kidney",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "Kidney",
          "TransportDirection": "ExcretionKidney",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Stomach",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "SmallIntestine",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Duodenum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "Duodenum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "UpperJejunum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "UpperJejunum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "LowerJejunum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "LowerJejunum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "UpperIleum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "UpperIleum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "LowerIleum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "LowerIleum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "LargeIntestine",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Caecum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "Caecum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "ColonAscendens",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "ColonAscendens",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "ColonTransversum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "ColonTransversum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "ColonDescendens",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "ColonDescendens",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "ColonSigmoid",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "ColonSigmoid",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Rectum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "Rectum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Periportal",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "Periportal",
          "TransportDirection": "ExcretionLiver",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Pericentral",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "Pericentral",
          "TransportDirection": "ExcretionLiver",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Lung",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Muscle",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Pancreas",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Skin",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Spleen",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "BloodCells",
          "TransportDirection": "EffluxBloodCellsToPlasma"
        },
        {
          "Name": "VascularEndothelium",
          "TransportDirection": "EffluxInterstitialToPlasma"
        }
      ]
    },
    {
      "Type": "Enzyme",
      "Species": "Human",
      "Molecule": "UGT1A4",
      "Category": "Healthy",
      "Parameters": [
        {
          "Path": "Organism|Bone|Intracellular|UGT1A4|Relative expression",
          "Value": 0.053151183
        },
        {
          "Path": "Organism|Brain|Intracellular|UGT1A4|Relative expression",
          "Value": 0.0585144121
        },
        {
          "Path": "Organism|Gonads|Intracellular|UGT1A4|Relative expression",
          "Value": 0.051483806
        },
        {
          "Path": "Organism|Heart|Intracellular|UGT1A4|Relative expression",
          "Value": 0.0550182787
        },
        {
          "Path": "Organism|Kidney|Intracellular|UGT1A4|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|UGT1A4|Relative expression",
          "Value": 0.2618621734
        },
        {
          "Path": "Organism|LargeIntestine|Mucosa|ColonAscendens|Intracellular|UGT1A4|Relative expression",
          "Value": 0.2618621734
        },
        {
          "Path": "Organism|LargeIntestine|Mucosa|ColonDescendens|Intracellular|UGT1A4|Relative expression",
          "Value": 0.2618621734
        },
        {
          "Path": "Organism|LargeIntestine|Mucosa|ColonSigmoid|Intracellular|UGT1A4|Relative expression",
          "Value": 0.2618621734
        },
        {
          "Path": "Organism|LargeIntestine|Mucosa|ColonTransversum|Intracellular|UGT1A4|Relative expression",
          "Value": 0.2618621734
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|UGT1A4|Relative expression",
          "Value": 0.5984749341
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|UGT1A4|Relative expression",
          "Value": 0.5984749341
        },
        {
          "Path": "Organism|Lung|Intracellular|UGT1A4|Relative expression",
          "Value": 0.0435540944
        },
        {
          "Path": "Organism|Muscle|Intracellular|UGT1A4|Relative expression",
          "Value": 0.0358344747
        },
        {
          "Path": "Organism|Pancreas|Intracellular|UGT1A4|Relative expression",
          "Value": 0.0787787225
        },
        {
          "Path": "Organism|Skin|Intracellular|UGT1A4|Relative expression",
          "Value": 0.1613838545
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|UGT1A4|Relative expression",
          "Value": 0.6918621406
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|UGT1A4|Relative expression",
          "Value": 0.6918621406
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|UGT1A4|Relative expression",
          "Value": 0.6918621406
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|UGT1A4|Relative expression",
          "Value": 0.6918621406
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|UGT1A4|Relative expression",
          "Value": 0.6918621406
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|UGT1A4|Relative expression",
          "Value": 0.6918621406
        },
        {
          "Path": "Organism|Spleen|Intracellular|UGT1A4|Relative expression",
          "Value": 0.0456003579
        },
        {
          "Path": "Organism|Stomach|Intracellular|UGT1A4|Relative expression",
          "Value": 0.1611559389
        },
        {
          "Path": "UGT1A4|Reference concentration",
          "Value": 1.0,
          "Unit": "µmol/l"
        },
        {
          "Path": "UGT1A4|t1/2 (intestine)",
          "Value": 1380.0,
          "Unit": "min"
        },
        {
          "Path": "UGT1A4|t1/2 (liver)",
          "Value": 2160.0,
          "Unit": "min"
        }
      ],
      "Localization": "Intracellular",
      "Ontogeny": {
        "Name": "UGT1A4"
      }
    },
    {
      "Type": "Transporter",
      "Species": "Human",
      "Molecule": "ABCB1",
      "Category": "Courtney et al 2003",
      "Parameters": [
        {
          "Path": "ABCB1|Reference concentration",
          "Value": 1.0,
          "Unit": "µmol/l"
        },
        {
          "Path": "ABCB1|t1/2 (intestine)",
          "Value": 1380.0,
          "Unit": "min"
        },
        {
          "Path": "ABCB1|t1/2 (liver)",
          "Value": 2160.0,
          "Unit": "min"
        },
        {
          "Path": "Organism|Bone|Intracellular|ABCB1|Relative expression",
          "Value": 0.0341950646
        },
        {
          "Path": "Organism|Brain|Intracellular|ABCB1|Relative expression",
          "Value": 0.1072855464
        },
        {
          "Path": "Organism|Gonads|Intracellular|ABCB1|Relative expression",
          "Value": 0.024559342
        },
        {
          "Path": "Organism|Heart|Intracellular|ABCB1|Relative expression",
          "Value": 0.059106933
        },
        {
          "Path": "Organism|Kidney|Intracellular|ABCB1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|ABCB1|Relative expression",
          "Value": 0.1562867215
        },
        {
          "Path": "Organism|LargeIntestine|Mucosa|ColonAscendens|Intracellular|ABCB1|Relative expression",
          "Value": 0.1562867215
        },
        {
          "Path": "Organism|LargeIntestine|Mucosa|ColonDescendens|Intracellular|ABCB1|Relative expression",
          "Value": 0.1562867215
        },
        {
          "Path": "Organism|LargeIntestine|Mucosa|ColonSigmoid|Intracellular|ABCB1|Relative expression",
          "Value": 0.1562867215
        },
        {
          "Path": "Organism|LargeIntestine|Mucosa|ColonTransversum|Intracellular|ABCB1|Relative expression",
          "Value": 0.1562867215
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|ABCB1|Relative expression",
          "Value": 0.2702702703
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|ABCB1|Relative expression",
          "Value": 0.2702702703
        },
        {
          "Path": "Organism|Lung|Intracellular|ABCB1|Relative expression",
          "Value": 0.0927144536
        },
        {
          "Path": "Organism|Muscle|Intracellular|ABCB1|Relative expression",
          "Value": 0.0180963572
        },
        {
          "Path": "Organism|Pancreas|Intracellular|ABCB1|Relative expression",
          "Value": 0.0200940071
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|ABCB1|Relative expression",
          "Value": 0.3960047004
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|ABCB1|Relative expression",
          "Value": 0.3960047004
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|ABCB1|Relative expression",
          "Value": 0.3960047004
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|ABCB1|Relative expression",
          "Value": 0.3960047004
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|ABCB1|Relative expression",
          "Value": 0.3960047004
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|ABCB1|Relative expression",
          "Value": 0.3960047004
        },
        {
          "Path": "Organism|Spleen|Intracellular|ABCB1|Relative expression",
          "Value": 0.1047003525
        },
        {
          "Path": "Organism|Stomach|Intracellular|ABCB1|Relative expression",
          "Value": 0.0367802585
        }
      ],
      "TransportType": "Efflux",
      "Expression": [
        {
          "Name": "Bone",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Brain",
          "TransportDirection": "EffluxBrainInterstitialToPlasma",
          "CompartmentName": "Plasma"
        },
        {
          "Name": "Brain",
          "TransportDirection": "EffluxBrainTissueToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "Fat",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Gonads",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Heart",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Kidney",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "Kidney",
          "TransportDirection": "ExcretionKidney",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Stomach",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "SmallIntestine",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Duodenum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "Duodenum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "UpperJejunum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "UpperJejunum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "LowerJejunum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "LowerJejunum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "UpperIleum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "UpperIleum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "LowerIleum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "LowerIleum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "LargeIntestine",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Caecum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "Caecum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "ColonAscendens",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "ColonAscendens",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "ColonTransversum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "ColonTransversum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "ColonDescendens",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "ColonDescendens",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "ColonSigmoid",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "ColonSigmoid",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
          "Name": "Rectum",
          "TransportDirection": "EffluxIntracellularToInterstitial",
          "CompartmentName": "Interstitial"
        },
        {
          "Name": "Rectum",
          "TransportDirection": "EffluxMucosaIntracellularToLumen",
          "CompartmentName": "Intracellular"
        },
        {
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          "Name": "Treat precipitated drug as",
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        {
          "Name": "Density (drug)",
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              "Name": "Solubility gain per charge",
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            "Description": "Pubchem _ Computed by PubChem 2.1 (PubChem release 2019.06.18)_https://pubchem.ncbi.nlm.nih.gov/compound/Posaconazole_assessed 02-12-2020"
          }
        },
        {
          "Name": "Molecular weight",
          "Value": 700.8,
          "Unit": "g/mol",
          "ValueOrigin": {
            "Source": "Internet",
            "Method": "Other",
            "Description": "Pubchem _ Computed by PubChem 2.1 (PubChem release 2019.06.18)_https://pubchem.ncbi.nlm.nih.gov/compound/Posaconazole_assessed 02-12-2020"
          }
        },
        {
          "Name": "Treat precipitated drug as",
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          "ValueOrigin": {
            "Source": "Unknown"
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        },
        {
          "Name": "Density (drug)",
          "Value": 0.3722022773,
          "Unit": "g/cm³",
          "ValueOrigin": {
            "Id": 32,
            "Source": "ParameterIdentification",
            "Method": "ParameterIdentification",
            "Description": "Value updated from 'Parameter Identification 5' on 2021-10-05 15:09"
          }
        },
        {
          "Name": "Enable supersaturation",
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          "ValueOrigin": {
            "Source": "Unknown"
          }
        }
      ]
    }
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        },
        {
          "Name": "Lag time",
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        },
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                "Source": "Unknown"
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          "Name": "Schema 3",
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              "FormulationKey": "Formulation",
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                },
                {
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          "Parameters": [
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              "Name": "Start time",
              "Value": 7.0,
              "Unit": "day(s)",
              "ValueOrigin": {
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                "Source": "Unknown"
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