diff --git a/changelogs/fragments/add_support_tgw_vpc.yml b/changelogs/fragments/add_support_tgw_vpc.yml
new file mode 100644
index 0000000000..ad448a26c1
--- /dev/null
+++ b/changelogs/fragments/add_support_tgw_vpc.yml
@@ -0,0 +1,3 @@
+---
+minor_changes:
+  - Add support for transit gateway vpc attachment module (https://github.com/ansible-collections/amazon.aws/pull/2314).
diff --git a/plugins/module_utils/ec2.py b/plugins/module_utils/ec2.py
index e488984649..c68c96f8f5 100644
--- a/plugins/module_utils/ec2.py
+++ b/plugins/module_utils/ec2.py
@@ -1520,6 +1520,49 @@ def get_sg_id(sg):
     return sec_group_id_list
 
 
+# EC2 Transit Gateway VPC Attachment Error handler
+class EC2TransitGatewayVPCAttachmentErrorHandler(AWSErrorHandler):
+    _CUSTOM_EXCEPTION = AnsibleEC2Error
+
+    @classmethod
+    def _is_missing(cls):
+        return is_boto3_error_code("InvalidGatewayID.NotFound")
+
+
+@EC2TransitGatewayVPCAttachmentErrorHandler.common_error_handler("describe transit gateway vpc attachments")
+@AWSRetry.jittered_backoff()
+def describe_transit_gateway_vpc_attachments(
+    client, **params: Dict[str, Union[List[str], bool, List[Dict[str, Union[str, List[str]]]]]]
+) -> List:
+    paginator = client.get_paginator("describe_transit_gateway_vpc_attachments")
+    return paginator.paginate(**params).build_full_result()["TransitGatewayVpcAttachments"]
+
+
+@EC2TransitGatewayVPCAttachmentErrorHandler.common_error_handler("create transit gateway vpc attachment")
+@AWSRetry.jittered_backoff()
+def create_transit_gateway_vpc_attachment(
+    client, **params: Dict[str, Union[List[str], bool, List[Dict[str, Union[str, List[str]]]]]]
+) -> Dict[str, Any]:
+    return client.create_transit_gateway_vpc_attachment(**params)["TransitGatewayVpcAttachment"]
+
+
+@EC2TransitGatewayVPCAttachmentErrorHandler.common_error_handler("modify transit gateway vpc attachment")
+@AWSRetry.jittered_backoff()
+def modify_transit_gateway_vpc_attachment(
+    client, **params: Dict[str, Union[List[str], bool, List[Dict[str, Union[str, List[str]]]]]]
+) -> Dict[str, Any]:
+    return client.modify_transit_gateway_vpc_attachment(**params)["TransitGatewayVpcAttachment"]
+
+
+@EC2TransitGatewayVPCAttachmentErrorHandler.deletion_error_handler("delete transit gateway vpc attachment")
+@AWSRetry.jittered_backoff()
+def delete_transit_gateway_vpc_attachment(client, transit_gateway_attachment_id: str) -> bool:
+    client.delete_transit_gateway_vpc_attachment(TransitGatewayAttachmentId=transit_gateway_attachment_id)[
+        "TransitGatewayVpcAttachment"
+    ]
+    return True
+
+
 def add_ec2_tags(client, module, resource_id, tags_to_set, retry_codes=None):
     """
     Sets Tags on an EC2 resource.
diff --git a/plugins/module_utils/waiters.py b/plugins/module_utils/waiters.py
index e3a3621dab..51213617f6 100644
--- a/plugins/module_utils/waiters.py
+++ b/plugins/module_utils/waiters.py
@@ -51,6 +51,52 @@
                 {"matcher": "error", "expected": "InvalidInternetGatewayID.NotFound", "state": "retry"},
             ],
         },
+        "TGWVpcAttachmentAvailable": {
+            "operation": "DescribeTransitGatewayVpcAttachments",
+            "delay": 5,
+            "maxAttempts": 120,
+            "acceptors": [
+                {
+                    "expected": "available",
+                    "matcher": "pathAll",
+                    "state": "success",
+                    "argument": "TransitGatewayVpcAttachments[].State",
+                },
+                {
+                    "state": "retry",
+                    "matcher": "pathAny",
+                    "argument": "TransitGatewayVpcAttachments[].State",
+                    "expected": "pending",
+                },
+                {"matcher": "error", "expected": "InvalidRouteTableID.NotFound", "state": "retry"},
+            ],
+        },
+        "TGWVpcAttachmentDeleted": {
+            "operation": "DescribeTransitGatewayVpcAttachments",
+            "delay": 5,
+            "maxAttempts": 120,
+            "acceptors": [
+                {
+                    "state": "retry",
+                    "matcher": "pathAll",
+                    "argument": "TransitGatewayVpcAttachments[].State",
+                    "expected": "deleting",
+                },
+                {
+                    "state": "success",
+                    "expected": "deleted",
+                    "matcher": "pathAll",
+                    "argument": "TransitGatewayVpcAttachments[].State",
+                },
+                {
+                    "expected": True,
+                    "matcher": "path",
+                    "state": "success",
+                    "argument": "length(TransitGatewayVpcAttachments[]) == `0`",
+                },
+                {"matcher": "error", "expected": "InvalidRouteTableID.NotFound", "state": "retry"},
+            ],
+        },
         "NetworkInterfaceAttached": {
             "operation": "DescribeNetworkInterfaces",
             "delay": 5,
@@ -774,6 +820,16 @@ def route53_model(name):
         ec2_model("InternetGatewayAttached"),
         core_waiter.NormalizedOperationMethod(ec2.describe_internet_gateways),
     ),
+    ("EC2", "transit_gateway_vpc_attachment_available"): lambda ec2: core_waiter.Waiter(
+        "transit_gateway_vpc_attachment_available",
+        ec2_model("TGWVpcAttachmentAvailable"),
+        core_waiter.NormalizedOperationMethod(ec2.describe_transit_gateway_vpc_attachments),
+    ),
+    ("EC2", "transit_gateway_vpc_attachment_deleted"): lambda ec2: core_waiter.Waiter(
+        "transit_gateway_vpc_attachment_deleted",
+        ec2_model("TGWVpcAttachmentDeleted"),
+        core_waiter.NormalizedOperationMethod(ec2.describe_transit_gateway_vpc_attachments),
+    ),
     ("EC2", "network_interface_attached"): lambda ec2: core_waiter.Waiter(
         "network_interface_attached",
         ec2_model("NetworkInterfaceAttached"),