diff --git a/ormar/fields/many_to_many.py b/ormar/fields/many_to_many.py
index 350fa3c38..bc212fcb6 100644
--- a/ormar/fields/many_to_many.py
+++ b/ormar/fields/many_to_many.py
@@ -124,6 +124,8 @@ def ManyToMany(  # type: ignore
 
     through_relation_name = kwargs.pop("through_relation_name", None)
     through_reverse_relation_name = kwargs.pop("through_reverse_relation_name", None)
+    is_through_relation_column_nullable = kwargs.pop("is_through_relation_column_nullable", None)
+    is_through_reverse_relation_column_nullable = kwargs.pop("is_through_reverse_relation_column_nullable", None)
 
     if through is not None and through.__class__ != ForwardRef:
         forbid_through_relations(cast(Type["Model"], through))
@@ -167,6 +169,8 @@ def ManyToMany(  # type: ignore
         skip_field=skip_field,
         through_relation_name=through_relation_name,
         through_reverse_relation_name=through_reverse_relation_name,
+        is_through_reverse_relation_column_nullable=is_through_reverse_relation_column_nullable,
+        is_through_relation_column_nullable=is_through_relation_column_nullable,
     )
 
     Field = type("ManyToMany", (ManyToManyField, BaseField), {})
diff --git a/ormar/models/helpers/sqlalchemy.py b/ormar/models/helpers/sqlalchemy.py
index b0ade1d02..d0e430b2d 100644
--- a/ormar/models/helpers/sqlalchemy.py
+++ b/ormar/models/helpers/sqlalchemy.py
@@ -44,10 +44,10 @@ def adjust_through_many_to_many_model(model_field: "ManyToManyField") -> None:
     )
 
     create_and_append_m2m_fk(
-        model=model_field.to, model_field=model_field, field_name=parent_name
+        model=model_field.to, model_field=model_field, field_name=parent_name, nullable=model_field.is_through_reverse_relation_column_nullable,
     )
     create_and_append_m2m_fk(
-        model=model_field.owner, model_field=model_field, field_name=child_name
+        model=model_field.owner, model_field=model_field, field_name=child_name, nullable=model_field.is_through_relation_column_nullable,
     )
 
     create_pydantic_field(parent_name, model_field.to, model_field)
@@ -58,7 +58,7 @@ def adjust_through_many_to_many_model(model_field: "ManyToManyField") -> None:
 
 
 def create_and_append_m2m_fk(
-    model: Type["Model"], model_field: "ManyToManyField", field_name: str
+    model: Type["Model"], model_field: "ManyToManyField", field_name: str, nullable: bool
 ) -> None:
     """
     Registers sqlalchemy Column with sqlalchemy.ForeignKey leading to the model.
@@ -88,6 +88,7 @@ def create_and_append_m2m_fk(
             name=f"fk_{model_field.through.Meta.tablename}_{model.Meta.tablename}"
             f"_{field_name}_{pk_alias}",
         ),
+        nullable=nullable,
     )
     model_field.through.Meta.columns.append(column)
     model_field.through.Meta.table.append_column(column)