diff --git a/.github/workflows/e2e_run_all.yaml b/.github/workflows/e2e_run_all.yaml
index d989593f1..c03619034 100644
--- a/.github/workflows/e2e_run_all.yaml
+++ b/.github/workflows/e2e_run_all.yaml
@@ -193,6 +193,45 @@ jobs:
       git_ref: ${{ inputs.git_ref }}
     secrets: inherit
 
+
+  # Run libvirt amd64 e2e tests, based on the mkosi image, if pull request labeled 'test_e2e_libvirt'
+  libvirt-amd64:
+    name: libvirt-amd64-tests
+    if: |
+      github.event_name == 'schedule' ||
+      github.event_name == 'workflow_dispatch' ||
+      contains(github.event.pull_request.labels.*.name, 'test_e2e_libvirt') ||
+      contains(github.event.pull_request.labels.*.name, 'test_e2e_libvirt_amd64')
+    needs: [podvm-mkosi-amd64, image, prep_install]
+    uses: ./.github/workflows/e2e_libvirt.yaml
+    with:
+      runner: ubuntu-24.04
+      caa_image: ${{ inputs.registry }}/cloud-api-adaptor:${{ inputs.caa_image_tag }}-dev
+      podvm_image: ${{ needs.podvm-mkosi-amd64.outputs.qcow2_oras_image }}
+      install_directory_artifact: install_directory
+      git_ref: ${{ inputs.git_ref }}
+      oras: true
+    secrets: inherit
+
+    # Run libvirt s390x e2e tests, based on the mkosi image, if pull request labeled 'test_e2e_libvirt'
+  libvirt-s390x:
+    name: libvirt-s390x-tests
+    if: |
+      github.event_name == 'schedule' ||
+      github.event_name == 'workflow_dispatch' ||
+      contains(github.event.pull_request.labels.*.name, 'test_e2e_libvirt') ||
+      contains(github.event.pull_request.labels.*.name, 'test_e2e_libvirt_s390x')
+    needs: [podvm-mkosi-s390x, image, prep_install]
+    uses: ./.github/workflows/e2e_libvirt.yaml
+    with:
+      runner: S390X
+      caa_image: ${{ inputs.registry }}/cloud-api-adaptor:${{ inputs.caa_image_tag }}-dev
+      podvm_image: ${{ needs.podvm-mkosi-s390x.outputs.qcow2_oras_image }}
+      install_directory_artifact: install_directory
+      git_ref: ${{ inputs.git_ref }}
+      oras: true
+    secrets: inherit
+
   # Run docker e2e tests if pull request labeled 'test_e2e_docker'
   docker:
     name: docker