DESCRIPTION

Package: immunarch
Type: Package
Title: Bioinformatics Analysis of T-Cell and B-Cell Immune Repertoires
Version: 0.6.6
Authors@R: c(
    person("Vadim I.", "Nazarov", , "vdm.nazarov@gmail.com", c("aut", "cre")),
    person("Vasily O.", "Tsvetkov", , role = "aut"),
    person("Eugene", "Rumynskiy", , role = "aut"),
    person("Anna", "Lorenc", , role = "ctb"),
    person("Daniel J.", "Moore", , role = "ctb"),
    person("Victor", "Greiff", , role = "ctb"),
    person("ImmunoMind", role = c("cph", "fnd"))
    )
Contact: support@immunomind.io
Description: A comprehensive framework for bioinformatics exploratory analysis of bulk and single-cell 
    T-cell receptor and antibody repertoires. It provides seamless data loading, analysis and 
    visualisation for AIRR (Adaptive Immune Receptor Repertoire) data, both bulk immunosequencing (RepSeq)
    and single-cell sequencing (scRNAseq). It implements most of the widely used AIRR analysis methods, 
    such as: clonality analysis, estimation of repertoire similarities in distribution of clonotypes 
    and gene segments, repertoire diversity analysis, annotation of clonotypes using external immune receptor 
    databases and clonotype tracking in vaccination and cancer studies. A successor to our
    previously published 'tcR' immunoinformatics package (Nazarov 2015) <doi:10.1186/s12859-015-0613-1>.
License: AGPL-3
URL: https://immunarch.com/, https://github.com/immunomind/immunarch
BugReports: https://github.com/immunomind/immunarch/issues
Imports:
    factoextra (>= 1.0.4),
    fpc,
    UpSetR (>= 1.4.0),
    pheatmap (>= 1.0.12),
    ggrepel (>= 0.8.0),
    reshape2 (>= 1.4.2),
    circlize,
    MASS (>= 7.3),
    Rtsne (>= 0.15),
    readr (>= 1.3.1),
    readxl (>= 1.3.1),
    shiny (>= 1.4.0),
    shinythemes,
    airr,
    ggseqlogo,
    stringr (>= 1.4.0),
    ggalluvial (>= 0.10.0),
    Rcpp (>= 1.0),
    magrittr,
    tibble (>= 2.0),
    methods,
    scales,
    ggpubr (>= 0.2),
    rlang (>= 0.4),
    plyr,
    dbplyr (>= 1.4.0)
Depends:
    R (>= 3.5.0),
    ggplot2 (>= 3.1.0),
    dplyr (>= 0.8.0),
    dtplyr (>= 1.0.0),
    data.table (>= 1.12.6),
    patchwork
LinkingTo: Rcpp
Suggests:
    knitr (>= 1.8),
    roxygen2 (>= 3.0.0),
    testthat (>= 2.1.0),
    pkgdown (>= 0.1.0),
    assertthat
VignetteBuilder: knitr
Encoding: UTF-8
RoxygenNote: 7.1.0
LazyData: true