diff --git a/CHANGELOG.md b/CHANGELOG.md
index 88124d3..dbd84ab 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -2,6 +2,11 @@
 
 [Semantic Versioning](https://semver.org/)
 
+## [2.10.4] - 2024-09-30
+### General
+- Dependency updates
+- Sequence Viewer: Adjust visuals of unobserved regions (HELP-21475)
+
 ## [2.10.3] - 2024-07-01
 ### Bug fixes
 - HELP-21267: don't apply pLDDT coloring to experimental structures
diff --git a/package-lock.json b/package-lock.json
index 00d15f3..ee203d5 100644
--- a/package-lock.json
+++ b/package-lock.json
@@ -11,7 +11,7 @@
             "dependencies": {
                 "@types/react": "^18.3.3",
                 "@types/react-dom": "^18.3.0",
-                "molstar": "^4.5.0",
+                "molstar": "^4.7.0",
                 "react": "^18.3.1",
                 "react-dom": "^18.3.1",
                 "rxjs": "^7.8.1",
@@ -21,23 +21,23 @@
                 "@typescript-eslint/eslint-plugin": "^7.17.0",
                 "@typescript-eslint/parser": "^7.17.0",
                 "buffer": "^6.0.3",
-                "concurrently": "^8.2.2",
+                "concurrently": "^9.0.1",
                 "cpx2": "^7.0.1",
                 "crypto-browserify": "^3.12.0",
                 "css-loader": "^7.1.2",
-                "eslint": "^8.57.0",
+                "eslint": "^8.57.1",
                 "extra-watch-webpack-plugin": "^1.0.3",
                 "file-loader": "^6.2.0",
                 "fs-extra": "^11.2.0",
                 "mini-css-extract-plugin": "^2.9.0",
                 "path-browserify": "^1.0.1",
                 "raw-loader": "^4.0.2",
-                "sass": "^1.77.8",
-                "sass-loader": "^14.2.1",
+                "sass": "^1.79.4",
+                "sass-loader": "^16.0.2",
                 "stream-browserify": "^3.0.0",
                 "style-loader": "^4.0.0",
-                "typescript": "^5.5.4",
-                "webpack": "^5.93.0",
+                "typescript": "^5.6.2",
+                "webpack": "^5.95.0",
                 "webpack-cli": "^5.1.4"
             }
         },
@@ -50,18 +50,6 @@
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-        "node_modules/@babel/runtime": {
-            "version": "7.22.5",
-            "resolved": "https://registry.npmjs.org/@babel/runtime/-/runtime-7.22.5.tgz",
-            "integrity": "sha512-ecjvYlnAaZ/KVneE/OdKYBYfgXV3Ptu6zQWmgEF7vwKhQnvVS6bjMD2XYgj+SNvQ1GfK/pjgokfPkC/2CO8CuA==",
-            "dev": true,
-            "dependencies": {
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             "resolved": "https://registry.npmjs.org/@discoveryjs/json-ext/-/json-ext-0.5.6.tgz",
@@ -119,21 +107,22 @@
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-            "resolved": "https://registry.npmjs.org/@eslint/js/-/js-8.57.0.tgz",
-            "integrity": "sha512-Ys+3g2TaW7gADOJzPt83SJtCDhMjndcDMFVQ/Tj9iA1BfJzFKD9mAUXT3OenpuPHbI6P/myECxRJrofUsDx/5g==",
+            "version": "8.57.1",
+            "resolved": "https://registry.npmjs.org/@eslint/js/-/js-8.57.1.tgz",
+            "integrity": "sha512-d9zaMRSTIKDLhctzH12MtXvJKSSUhaHcjV+2Z+GK+EEY7XKpP5yR4x+N3TAcHTcu963nIr+TMcCb4DBCYX1z6Q==",
             "dev": true,
             "engines": {
                 "node": "^12.22.0 || ^14.17.0 || >=16.0.0"
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         "node_modules/@humanwhocodes/config-array": {
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-            "resolved": "https://registry.npmjs.org/@humanwhocodes/config-array/-/config-array-0.11.14.tgz",
-            "integrity": "sha512-3T8LkOmg45BV5FICb15QQMsyUSWrQ8AygVfC7ZG32zOalnqrilm018ZVCw0eapXux8FtA33q8PSRSstjee3jSg==",
+            "version": "0.13.0",
+            "resolved": "https://registry.npmjs.org/@humanwhocodes/config-array/-/config-array-0.13.0.tgz",
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+            "deprecated": "Use @eslint/config-array instead",
             "dev": true,
             "dependencies": {
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+                "@humanwhocodes/object-schema": "^2.0.3",
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@@ -155,9 +144,10 @@
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-            "resolved": "https://registry.npmjs.org/@humanwhocodes/object-schema/-/object-schema-2.0.2.tgz",
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+            "version": "2.0.3",
+            "resolved": "https://registry.npmjs.org/@humanwhocodes/object-schema/-/object-schema-2.0.3.tgz",
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+            "deprecated": "Use @eslint/object-schema instead",
             "dev": true
         },
         "node_modules/@isaacs/cliui": {
@@ -510,26 +500,6 @@
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-            "resolved": "https://registry.npmjs.org/@types/eslint-scope/-/eslint-scope-3.7.3.tgz",
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-            "dev": true,
-            "dependencies": {
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@@ -603,9 +573,9 @@
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+            "resolved": "https://registry.npmjs.org/@types/node/-/node-18.19.54.tgz",
+            "integrity": "sha512-+BRgt0G5gYjTvdLac9sIeE0iZcJxi4Jc4PV5EUzqi+88jmQLr+fRZdv2tCTV7IHKSGxM6SaLoOXQWWUiLUItMw==",
             "dependencies": {
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@@ -1273,19 +1243,6 @@
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-        "node_modules/anymatch": {
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-            "resolved": "https://registry.npmjs.org/anymatch/-/anymatch-3.1.2.tgz",
-            "integrity": "sha512-P43ePfOAIupkguHUycrc4qJ9kz8ZiuOUijaETwX7THt0Y/GNK7v0aa8rY816xWjZ7rJdA5XdMcpVFTKMq+RvWg==",
-            "dev": true,
-            "dependencies": {
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-                "picomatch": "^2.0.4"
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@@ -1453,15 +1410,6 @@
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@@ -1523,9 +1471,9 @@
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-            "resolved": "https://registry.npmjs.org/body-parser/-/body-parser-1.20.2.tgz",
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+            "resolved": "https://registry.npmjs.org/body-parser/-/body-parser-1.20.3.tgz",
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@@ -1535,7 +1483,7 @@
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                 "iconv-lite": "0.4.24",
                 "on-finished": "2.4.1",
-                "qs": "6.11.0",
+                "qs": "6.13.0",
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@@ -1823,12 +1771,18 @@
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-                "get-intrinsic": "^1.0.2"
+                "es-define-property": "^1.0.0",
+                "es-errors": "^1.3.0",
+                "function-bind": "^1.1.2",
+                "get-intrinsic": "^1.2.4",
+                "set-function-length": "^1.2.1"
+            },
+            "engines": {
+                "node": ">= 0.4"
             },
             "funding": {
                 "url": "https://github.com/sponsors/ljharb"
@@ -1991,42 +1945,18 @@
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-            "funding": [
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-                    "url": "https://paulmillr.com/funding/"
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-                "is-glob": "~4.0.1",
-                "normalize-path": "~3.0.0",
-                "readdirp": "~3.6.0"
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@@ -2237,7 +2165,7 @@
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+                "es-errors": "^1.3.0",
+                "gopd": "^1.0.1"
+            },
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+            "funding": {
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@@ -14273,6 +14160,19 @@
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@@ -14319,13 +14219,14 @@
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@@ -14810,9 +14705,9 @@
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@@ -14892,9 +14787,9 @@
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@@ -15108,7 +15002,7 @@
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diff --git a/package.json b/package.json
index e8e1f3d..a2ced30 100644
--- a/package.json
+++ b/package.json
@@ -40,29 +40,29 @@
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-        "sass-loader": "^14.2.1",
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         "style-loader": "^4.0.0",
-        "typescript": "^5.5.4",
-        "webpack": "^5.93.0",
+        "typescript": "^5.6.2",
+        "webpack": "^5.95.0",
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-        "molstar": "^4.5.0",
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         "react-dom": "^18.3.1",
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