diff --git a/Client/loader/CInstallManager.cpp b/Client/loader/CInstallManager.cpp
index c16c3afcec..8a9d3bd786 100644
--- a/Client/loader/CInstallManager.cpp
+++ b/Client/loader/CInstallManager.cpp
@@ -1269,17 +1269,31 @@ SString CInstallManager::_ProcessAppCompatChecks()
     }
 
     // Windows 7: Fix invalid GameUX URL (which causes rundll32.exe to use excessive CPU)
-    WString strUrlKey = L"SOFTWARE\\Classes\\Local Settings\\Software\\Microsoft\\Windows\\GameUX\\ServiceLocation";
-    WString strUrlItem = L"Games";
-    WString strUrlValue = ReadCompatibilityEntries(strUrlItem, strUrlKey, HKEY_CURRENT_USER, 0);
-    if (!strUrlValue.empty())
     {
-        WriteDebugEvent(SString("GameUX ServiceLocation was '%s'", *ToUTF8(strUrlValue)));
-        if (strUrlValue.ContainsI(L":"))
+        WString strUrlKey = L"SOFTWARE\\Classes\\Local Settings\\Software\\Microsoft\\Windows\\GameUX\\ServiceLocation";
+        WString strUrlItem = L"Games";
+        WString strUrlValue = ReadCompatibilityEntries(strUrlItem, strUrlKey, HKEY_CURRENT_USER, 0);
+        if (!strUrlValue.empty())
         {
-            strUrlValue = L"disabled";            // Can be anything not containing `:`
-            if (!WriteCompatibilityEntries(strUrlItem, strUrlKey, HKEY_CURRENT_USER, 0, strUrlValue))
-                bTryAdmin = true;
+            WriteDebugEvent(SString("GameUX ServiceLocation was '%s'", *ToUTF8(strUrlValue)));
+            if (strUrlValue.ContainsI(L":"))
+            {
+                strUrlValue = L"disabled";            // Can be anything not containing `:`
+                if (!WriteCompatibilityEntries(strUrlItem, strUrlKey, HKEY_CURRENT_USER, 0, strUrlValue))
+                    bTryAdmin = true;
+            }
+        }
+    }
+
+    // Windows 10: Disable multi-threaded loading of DLLs.
+    {
+        DWORD   maxLoaderThreads{};
+        LPCWSTR imageFileExecutionOptions = L"SOFTWARE\\Microsoft\\Windows NT\\CurrentVersion\\Image File Execution Options\\" GTA_EXE_NAME;
+        RegQueryInteger(HKEY_LOCAL_MACHINE, imageFileExecutionOptions, L"MaxLoaderThreads", maxLoaderThreads);
+
+        if (maxLoaderThreads != 1 && !RegWriteInteger(HKEY_LOCAL_MACHINE, imageFileExecutionOptions, L"MaxLoaderThreads", 1))
+        {
+            bTryAdmin = true;
         }
     }
 
diff --git a/Client/loader/Utils.cpp b/Client/loader/Utils.cpp
index db8cde4125..9d3ead9eba 100644
--- a/Client/loader/Utils.cpp
+++ b/Client/loader/Utils.cpp
@@ -2178,6 +2178,32 @@ bool IsNativeArm64Host()
     return isArm64;
 }
 
+bool RegQueryInteger(HKEY rootKey, LPCWSTR keyName, LPCWSTR valueName, DWORD& value)
+{
+    value = {};
+
+    HKEY key{};
+    if (RegOpenKeyExW(rootKey, keyName, 0, KEY_READ, &key) != ERROR_SUCCESS)
+        return false;
+
+    DWORD   valueType = REG_DWORD;
+    DWORD   valueSize = sizeof(value);
+    LSTATUS status = RegQueryValueExW(key, valueName, nullptr, &valueType, reinterpret_cast<LPBYTE>(&value), &valueSize);
+    RegCloseKey(key);
+    return status == ERROR_SUCCESS;
+}
+
+bool RegWriteInteger(HKEY rootKey, LPCWSTR keyName, LPCWSTR valueName, DWORD value)
+{
+    HKEY key{};
+    if (RegCreateKeyExW(rootKey, keyName, 0, 0, REG_OPTION_NON_VOLATILE, KEY_WRITE, nullptr, &key, nullptr) != ERROR_SUCCESS)
+        return false;
+
+    LSTATUS status = RegSetValueExW(key, valueName, 0, REG_DWORD, reinterpret_cast<LPBYTE>(&value), sizeof(value));
+    RegCloseKey(key);
+    return status == ERROR_SUCCESS;
+}
+
 //////////////////////////////////////////////////////////
 //
 // ReadCompatibilityEntries
diff --git a/Client/loader/Utils.h b/Client/loader/Utils.h
index ab7530f4f2..be0685a83c 100644
--- a/Client/loader/Utils.h
+++ b/Client/loader/Utils.h
@@ -156,6 +156,16 @@ bool IsErrorCodeLoggable(const std::error_code& ec);
  */
 bool IsNativeArm64Host();
 
+/**
+ * @brief Queries the integer value of a specific value item from the registry.
+ */
+bool RegQueryInteger(HKEY rootKey, LPCWSTR keyName, LPCWSTR valueName, DWORD& value);
+
+/**
+ * @brief Writes an integer value to a specific value item in the registry.
+ */
+bool RegWriteInteger(HKEY rootKey, LPCWSTR keyName, LPCWSTR valueName, DWORD value);
+
 // Return false on read failure
 template <class T>
 bool ReadFileValue(const SString& strFilename, T& value, uint uiOffset)
diff --git a/Shared/installer/nightly.nsi b/Shared/installer/nightly.nsi
index d3d7759cdd..7890e37fdc 100644
--- a/Shared/installer/nightly.nsi
+++ b/Shared/installer/nightly.nsi
@@ -369,6 +369,9 @@ Function .onInstSuccess
 
     WriteRegStr HKLM "SOFTWARE\Multi Theft Auto: San Andreas All\Common" "GTA:SA Path" $GTA_DIR
     WriteRegStr HKLM "SOFTWARE\Multi Theft Auto: San Andreas All\${0.0}" "Last Install Location" $INSTDIR
+
+    # Add 'MaxLoaderThreads' DWORD value for gta_sa.exe to disable multi-threaded loading of DLLs.
+    WriteRegDWORD HKLM "SOFTWARE\Microsoft\Windows NT\CurrentVersion\Image File Execution Options\gta_sa.exe" "MaxLoaderThreads" 1
 	
 	# Initilize variables holding paths and names
 	Call MTAInitFileNamesAndPaths
@@ -1142,6 +1145,10 @@ Section Uninstall
             DeleteRegKey HKCR "mtasa"
         ${EndIf}
 
+        # Remove 'MaxLoaderThreads' DWORD value for gta_sa.exe.
+        DeleteRegValue HKLM "SOFTWARE\Microsoft\Windows NT\CurrentVersion\Image File Execution Options\gta_sa.exe" "MaxLoaderThreads"
+        DeleteRegKey /ifempty HKLM "SOFTWARE\Microsoft\Windows NT\CurrentVersion\Image File Execution Options\gta_sa.exe"
+
         ${GameExplorer_RemoveGame} ${GUID}
 
         ; Delete client shortcuts