About Me (CV)
Postdoctoral fellow
Dept. of Biotechnology
College of Life Science and Biotechnology
Yonsei University
Seoul 03722, KOREA.
Tel: (+82)-2-2123-7292
Phone: (+82)-10-3319-6382
E-mail: sungjaeyoon@yonsei.ac.kr, o3wodbs@gmail.com
Github: https://github.com/JAEYOONSUNG/
- Department of Biotechnology, Yonsei University, Seoul, Korea
Advisor: Dong-Woo Lee
- Department of Biotechnology, Yonsei University, Seoul, Korea
Thesis Advisor: Dong-Woo Lee
Thesis: “Elucidation of thermophily for Bacillales using a phylogenomic approach and the development of a thermophilic platform host”
- School of Applied Life Science, Kyungpook National University, Daegu, Korea
- Microbial adaptation to extreme environments
- Physiology
- Setup genetic tools for non-model bacteria
- Applications of extremophiles for sustainable process
- Protein evolution
- Structural basis functional analysis
- Epigenomics
- Precision DNA alteration tools
- Development of a simplified analysis pipeline
- Big data analysis in multi-omics
- Ganbat, S., Ganbat, D., Sung, J.Y., Kim, S,B., Lee, D.W., and Lee, S.J.* (2024) Complete genome sequence of polyhydroxyalkaonate accumulating bacterium Schlegelella aquatica HS-12-14 isolated from Korean hot spring. Microbiol. Resour. Announc.
- Sung, J.Y.£, Ganbat, D.£, Kim, S,B., Lee, S.J., and Lee, D.W. (2024) Complete genome sequences of Geobacillus stearothermophilus strains EF60045 and SJEF4-2 from Korean hot springs. Microbiol. Resour. Announc. e00573-24.
- Joo, Y.H. £, Sung, J.Y.£, Shin, S.M., Park, S.J., Kim, K.S., Park, K.D., Kim, S.B., and Lee, D.W.* (2023) A retroaldol reaction prompted the evolvability of a phosphotransferase system for the utilization of a rare sugar. Microbiol. Spectr. 11(2) e03660-22.
- Sung, J.Y. £, Lee, Y.J. £, Cho, Y.J., Lee, S.J., Lee, H.S., Bae, J.W., Shin, J.H., Koh, H., Kim, H.J., and Lee, D.W. (2021) A large scale metagenomic study for enzyme profiles using the focused identification of the NGS-based definitive enzyme research (FINDER) strategy. Biotechnol. Bioeng. 118: 4360-4374. (Editor’s choice articles/Front cover paper)
- Jin, H.S. £, Dhanasingh, I. £, Sung, J.Y., La, J.W., Lee, Y., Lee, E.M., Kang, Y.J., Lee, D.Y., Lee, S.H., and Lee, D.W. (2021) The sulfur formation system mediating extracellular cysteine-cystine recycling in Fervidobacterium islandicum AW-1 is associated with keratin degradation. Microb, Biotechnol. 14, 938-952.
- Dhanasingh, I.£, Sung, J.Y.£, Ghosh, S., La, J.W., Kang, E.J., Lee, D.W., and Lee, S.H.*. (2021) Structure of oxidized pyrrolidone carboxypeptidase from Fervidobacterium islandicum AW-1 reveals unique structural features for thermostability and keratinolysis. Biochem. Biophys. Res. Commun. 540, 101-107.
- Kang, E.J., Jin, H.S, La, J.W., Sung, J.Y., Park, S.Y., Kim, W.C., and Lee, D.W.* (2020) Identification of keratinases from Fervidobacterium islandicum AW-1 using dynamic gene expression profiling. Microb. Biotechnol. 13, 442-457.
- Kim, K.N., Yang, J.O., Sung, J.Y., Lee, J.Y., Park, J.S., Lee, H.S., Lee, B.H., Ren, Y., Lee, D.W., and Lee, S.E. (2019) Minimization of energy transduction confers resistance to phosphine in crop arthropods. Sci. Rep. 9, 14605.
- Sung, J.Y., Lee, M.H., Kim, H.B., Ganbat, D., Cho, H.W., Lee, S.J., Kim, S.B.,, and Lee, D.W.. Harnessing Geobacillus stearothermophilus for enhanced thermophilic enzyme production and evolution.
- Sung, J.Y.,£, Yoo, Y.K.£, Lee, M.H., Yang, S.Y., Cho, H.S.and Lee, D.W.. Structural basis mechanism of novel Type III Restriction-Methylation systems in hyperthermophilic Fervidobacterium islandicum AW-1.
- Sung, J.Y.,£, Kim, J.Y.£, Lee, E.M., Baek, J.H., Lee, Y.J., Jin, H.S., Kim, B.C., Lee, D.Y.,, and Lee, D.W.,. Molecular insights into keratin degradation by Fervidobacterium islandicum AW-1: An evolutionary perspective on bacterial resilience to starvation.
- Sung, J.Y.,£, Shin.S.M.,£, Hoang, N.K.Q., Dhanasingh, I., Yoo, K.Y., Lim, H.C., Cao, T., Lee, S.J., Kim, S.B., Lee, S.H.,, and Lee, D.W.,. Metal-mediated intermolecular interactions contribute to the thermostabilization of primordial sugar isomerases.
- Sung, J.Y., Park, M.K., Park, J.S., Lee, M.H., Lee, Y.J., Kim, K.S., Lee, S.J., and Lee, D.W.,*. Evolutionary genetic traits for thermal adaptation using a pan-genomic approach in the order Bacillales.
- DNMB, a combined scripts-based pipeline for comprehensive genomics analysis of non-model bacteria (https://github.com/JAEYOONSUNG/DNMB/)
- GenomeDrawer, (https://github.com/JAEYOONSUNG/GenomeDrawer/)
- BPGAconvert, (https://github.com/JAEYOONSUNG/BPGAconvert/)
- OGRIparser, (https://github.com/JAEYOONSUNG/OGRIparser/)
- FINDER, a large-scale metagenomic study for enzyme profiles using the focused identification of the NGS-based definitive enzyme research (FINDER) strategy (https://github.com/JAEYOONSUNG/FINDER/)
- mRNAcal, a comprehensive R Package for streamlined mRNA region extraction and RNA secondary structure analysis with the viennaRNA (https://github.com/JAEYOONSUNG/mRNAcal/)
- Best Poster Award, 2017 International Meeting of the Microbiology Society of Korea (MSK)
- BK21 FOUR Best Research Award, BK21 Yonsei education & Research center for biosystems (2021.01)
- BK21 FOUR Best Research Award, BK21 Yonsei education & Research center for biosystems (2022.01)
- BK21 FOUR Best Research Award, BK21 Yonsei education & Research center for biosystems (2024.01)
- Extremophiles 2024 (2024.09)
- A Strategic Blueprint for the Domestication of Geobacillus stearothermophilus as a Thermophilic Platform Cell using the DNMB Suite, MSK 2024, Jeju, Korea
- Large-Scale Metagenomic Study for Enzyme Profiling Using the Focused Identification of the NGS-Based Definitive Enzyme Research (FINDER) Strategy, 2021 BK21 symposium, Yonsei University, Seoul, Korea
- A Strategic Blueprint for the Domestication of Geobacillus stearothermophilus as a Thermophilic Platform Cell using the DNMB Suite, Extremophiles 2024, Loutraki, Greece
- Comparative Genomics and Physiological Characterization of Geobacillus species Reveal Unique Traits in G. stearothermophilus for Industrial Applications, Thermophiles 2023, Bangor, Wales
- Conserved Sequence-Based Recombination of Homologous Sugar Isomerases from Diverse Species Reveals Genetic Traits for Environmental Adaptation, SIMB 2022, San Francisco, United States of America
- Conserved Sequence-Based Recombination of Homologous Sugar Isomerases from Diverse Species Reveals Genetic Traits for Environmental Adaptation, KMB 2022, Korea
- Conserved Sequence-Based Recombination of Homologous Sugar Isomerases from Diverse Species Reveals Genetic Traits for Environmental Adaptation, KSBB 2021, Jeju, Korea
- Intervening variable sequence regions of homologous sugar isomerases define thermal adaptation traits, KMB 2021, Busan, Korea
- High-resolution crystal structures of homologous alkalophilic and acidophilic L-arabinose isomerases unveil the catalytic mechanism and pH-dependent activity, KoSFoST 2019, Incheon, Korea
- The Sulfur Formation System Mediating Fe-S Cluster Assembly in Fervidobacterium islandicum AW-1 is Associated with Keratin Degradation, Extremophiles 2018, Ischia, Italy
- Development of a Cell Growth-Based High-throughput Screening System for Engineering the Substrate Specificity of Sugar Isomerase, Extremophiles 2018, Ischia, Italy
- Development of a Cell Growth-Based High-throughput Screening System for Engineering of the Substrate Specificity of L-Arabinose Isomerase, MSK 2017, Busan, Korea
- A recombinant strain having modified sugar metabolic pathway and method for screening sugar isomerase using same. US 2020/0087647 A1. Mar. 19, 2020
- Composition for epimerization of non-phosphorylated hexose comprising sugar epimerases derived from thermophiles. US 9914984 B2. Mar. 13, 2018 (EP3072403A1/CN105916389A).
- 희귀당 비대사성 균주의 희귀당 자화능 결정 유전자군 제공방법(등록:10-2590888), 2023.10.13.
- 변형된 당 대사 경로를 갖는 재조합 균주를 이용한 당이성화 효소의 스크리닝 방법(등록:10-2007890), 2019. 7.31.
- 변형된 당 대사 경로를 갖는 재조합 균주 및 이를 이용한 당이성화 효소의 스크리닝 방법(등록:10-1979213), 2019. 5.10.
- 2018 R Workshop, Seoul University, Seoul, Korea
- 2019 Workshop on Smart Cell Factory Design, Sogang University, Seoul, Korea
- 2022 Winter Data Science Workshop, Yonsei University, Seoul, Korea
- Python Programming and Web Crawling, Data Literacy using R, Machine Learning with Python, Introduction to Deep Learning with Python, Applied Deep Learning with Python
