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Development of a genome-wide DNA methylation reference panel for constituent cell types of Bronchoalveolar Lavage.

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JovMaksimovic/paed-BAL-meth-ref

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Methylation profiling of purified cell types from paediatric Bronchoalveolar Lavage (BAL)

This site contains the results of the analyses performed to develop a genome-wide DNA methylation reference panel of the clinically-relevant constituent cell types of paediatric BAL collected from children with cystic fibrosis. This reference panel can be used in conjunction with appropriate reference-based deconvolution methods to adjust for cell composition in epigenome-wide association studies of pulmonary health and disease, particularly in paediatric cohorts.

All aspects of the analysis can be explored here.

The code in this analysis is covered by the MIT license and the written content is covered by a Creative Commons CC-BY license.

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Development of a genome-wide DNA methylation reference panel for constituent cell types of Bronchoalveolar Lavage.

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