feat!: use reference service to provide assembly ID

etc/example.env

@@ -39,8 +39,8 @@ GOHAN_API_IMAGE=gohan-api
 GOHAN_API_VERSION=latest
 
 GOHAN_API_BUILDER_BASE_IMAGE=golang:1.21-bookworm
-GOHAN_API_DEV_BASE_IMAGE=ghcr.io/bento-platform/bento_base_image:golang-debian-2023.11.10
-GOHAN_API_PROD_BASE_IMAGE=ghcr.io/bento-platform/bento_base_image:plain-debian-2023.11.10
+GOHAN_API_DEV_BASE_IMAGE=ghcr.io/bento-platform/bento_base_image:golang-debian-2023.12.01
+GOHAN_API_PROD_BASE_IMAGE=ghcr.io/bento-platform/bento_base_image:plain-debian-2023.12.01
 
 GOHAN_API_CONTAINER_NAME=gohan-api
 GOHAN_API_SERVICE_HOST=0.0.0.0

src/api/contexts/contexts.go

@@ -25,7 +25,7 @@ type (
 
 	// Convenient storage for relevant http context data
 	QueryParameters struct {
-		AssemblyId constants.AssemblyId
+		AssemblyId string
 		Alleles    []string
 		Chromosome string
 		Genotype   constants.GenotypeQuery

src/api/middleware/assemblyMiddleware.go

@@ -2,8 +2,6 @@ package middleware
 
 import (
 	"gohan/api/contexts"
-	"gohan/api/models/constants"
-	assid "gohan/api/models/constants/assembly-id"
 	"net/http"
 
 	"github.com/labstack/echo"
@@ -16,14 +14,14 @@ func MandateAssemblyIdAttribute(next echo.HandlerFunc) echo.HandlerFunc {
 	return func(c echo.Context) error {
 		// check for assemblyId query parameter
 		assemblyId := c.QueryParam("assemblyId")
-		if len(assemblyId) == 0 || !assid.IsKnownAssemblyId(assemblyId) {
-			// if no id was provided, or it was invalid, return an error
-			return echo.NewHTTPError(http.StatusBadRequest, "Missing or unknown assemblyId!")
+		if len(assemblyId) == 0 {
+			// if no id was provided, return an error
+			return echo.NewHTTPError(http.StatusBadRequest, "Missing assemblyId!")
 		}
 
 		// forward a type-safe value down the pipeline
 		gc := c.(*contexts.GohanContext)
-		gc.AssemblyId = constants.AssemblyId(assemblyId)
+		gc.AssemblyId = assemblyId
 
 		return next(gc)
 	}

src/api/models/constants/assembly-id/main.go

@@ -1,42 +1,6 @@
 package assemblyId
 
-import (
-	"gohan/api/models/constants"
-	"strings"
-)
-
 const (
-	Unknown constants.AssemblyId = "Unknown"
-
-	GRCh38 constants.AssemblyId = "GRCh38"
-	GRCh37 constants.AssemblyId = "GRCh37"
-	NCBI36 constants.AssemblyId = "NCBI36"
-	NCBI35 constants.AssemblyId = "NCBI35"
-	NCBI34 constants.AssemblyId = "NCBI34"
-	Other  constants.AssemblyId = "Other"
+	GRCh38 string = "GRCh38"
+	GRCh37 string = "GRCh37"
 )
-
-func CastToAssemblyId(text string) constants.AssemblyId {
-	switch strings.ToLower(text) {
-	case "grch38":
-		return GRCh38
-	case "grch37":
-		return GRCh37
-	case "ncbi36":
-		return NCBI36
-	case "ncbi35":
-		return NCBI35
-	case "ncbi34":
-		return NCBI34
-	case "other":
-		return Other
-	default:
-		return Unknown
-	}
-}
-
-func IsKnownAssemblyId(text string) bool {
-	// attempt to cast to assemblyId and
-	// return if unknown assemblyId
-	return CastToAssemblyId(text) != Unknown
-}

src/api/models/dtos/main.go

@@ -1,7 +1,6 @@
 package dtos
 
 import (
-	"gohan/api/models/constants"
 	"gohan/api/models/indexes"
 	"time"
 )
@@ -21,11 +20,11 @@ type VariantCountReponse struct {
 }
 
 type VariantResult struct {
-	Query      string               `json:"query,omitempty"`
-	AssemblyId constants.AssemblyId `json:"assembly_id"`
-	Chromosome string               `json:"chromosome"`
-	Start      int                  `json:"start"`
-	End        int                  `json:"end"`
+	Query      string `json:"query,omitempty"`
+	AssemblyId string `json:"assembly_id"`
+	Chromosome string `json:"chromosome"`
+	Start      int    `json:"start"`
+	End        int    `json:"end"`
 }
 
 type VariantGetResult struct {
@@ -54,9 +53,9 @@ type VariantCall struct {
 	Alleles      []string `json:"alleles,omitempty"`
 	// TODO: GenotypeProbability, PhredScaleLikelyhood ?
 
-	AssemblyId constants.AssemblyId `json:"assemblyId,omitempty"`
-	Dataset    string               `json:"dataset,omitempty"`
-	DocumentId string               `json:"documentId,omitempty"`
+	AssemblyId string `json:"assemblyId,omitempty"`
+	Dataset    string `json:"dataset,omitempty"`
+	DocumentId string `json:"documentId,omitempty"`
 }
 
 // --- Dataset

src/api/models/indexes/main.go

@@ -18,10 +18,10 @@ type Variant struct {
 
 	Sample Sample `json:"sample"`
 
-	FileId      string       `json:"fileId"`
-	Dataset     string       `json:"dataset"`
-	AssemblyId  c.AssemblyId `json:"assemblyId"`
-	CreatedTime time.Time    `json:"createdTime"`
+	FileId      string    `json:"fileId"`
+	Dataset     string    `json:"dataset"`
+	AssemblyId  string    `json:"assemblyId"`
+	CreatedTime time.Time `json:"createdTime"`
 }
 
 type Info struct {
@@ -51,9 +51,9 @@ type Genotype struct {
 }
 
 type Gene struct {
-	Name       string       `json:"name"`
-	Chrom      string       `json:"chrom"`
-	Start      int          `json:"start"`
-	End        int          `json:"end"`
-	AssemblyId c.AssemblyId `json:"assemblyId"`
+	Name       string `json:"name"`
+	Chrom      string `json:"chrom"`
+	Start      int    `json:"start"`
+	End        int    `json:"end"`
+	AssemblyId string `json:"assemblyId"`
 }

src/api/mvc/genes/main.go

@@ -6,7 +6,6 @@ import (
 	"crypto/tls"
 	"fmt"
 	"gohan/api/contexts"
-	"gohan/api/models/constants"
 	assemblyId "gohan/api/models/constants/assembly-id"
 	"gohan/api/models/constants/chromosome"
 	"gohan/api/models/dtos"
@@ -51,15 +50,15 @@ func GenesIngest(c echo.Context) error {
 			http.DefaultTransport.(*http.Transport).TLSClientConfig = &tls.Config{InsecureSkipVerify: true}
 		}
 
-		assemblyIdMap := map[constants.AssemblyId]string{
+		assemblyIdMap := map[string]string{
 			assemblyId.GRCh38: "gencode.v38.annotation.gtf",
 			assemblyId.GRCh37: "gencode.v19.annotation.gtf",
 			// SKIP
 			// assemblyId.NCBI36: "hg18",
 			// assemblyId.NCBI35: "hg17",
 			// assemblyId.NCBI34: "hg16",
 		}
-		assemblyIdGTFUrlMap := map[constants.AssemblyId]string{
+		assemblyIdGTFUrlMap := map[string]string{
 			assemblyId.GRCh38: "http://ftp.ebi.ac.uk/pub/databases/gencode/Gencode_human/release_38/gencode.v38.annotation.gtf.gz",
 			assemblyId.GRCh37: "http://ftp.ebi.ac.uk/pub/databases/gencode/Gencode_human/release_19/gencode.v19.annotation.gtf.gz",
 			// SKIP
@@ -79,7 +78,7 @@ func GenesIngest(c echo.Context) error {
 				CreatedAt: fmt.Sprintf("%v", time.Now()),
 			}
 
-			go func(_assId constants.AssemblyId, _fileName string, _assemblyWg *sync.WaitGroup, reqStat *ingest.GeneIngestRequest) {
+			go func(_asmId string, _fileName string, _assemblyWg *sync.WaitGroup, reqStat *ingest.GeneIngestRequest) {
 				defer _assemblyWg.Done()
 
 				var (
@@ -89,7 +88,7 @@ func GenesIngest(c echo.Context) error {
 				gtfFile, err := os.Open(fmt.Sprintf("%s/%s", gtfPath, _fileName))
 				if err != nil {
 					// Download the file
-					fullURLFile := assemblyIdGTFUrlMap[_assId]
+					fullURLFile := assemblyIdGTFUrlMap[_asmId]
 
 					handleHardErr := func(err error) {
 						msg := "Something went wrong:  " + err.Error()
@@ -193,13 +192,13 @@ func GenesIngest(c echo.Context) error {
 				defer gtfFile.Close()
 
 				// clean out genes currently in elasticsearch by assembly id
-				fmt.Printf("Cleaning out %s gene documents from genes index (if any)\n", string(_assId))
-				esRepo.DeleteGenesByAssemblyId(cfg, es7Client, _assId)
+				fmt.Printf("Cleaning out %s gene documents from genes index (if any)\n", string(_asmId))
+				esRepo.DeleteGenesByAssemblyId(cfg, es7Client, _asmId)
 
 				fileScanner := bufio.NewScanner(gtfFile)
 				fileScanner.Split(bufio.ScanLines)
 
-				fmt.Printf("Ingesting %s\n", string(_assId))
+				fmt.Printf("Ingesting %s\n", string(_asmId))
 				reqStat.State = ingest.Running
 				iz.GeneIngestRequestChan <- reqStat
 
@@ -222,7 +221,7 @@ func GenesIngest(c echo.Context) error {
 					go func(rowText string, _chromHeaderKey int,
 						_startKey int, _endKey int,
 						_nameHeaderKeys []int, _geneNameHeaderKeys []int,
-						_assId constants.AssemblyId,
+						_assId string,
 						_gwg *sync.WaitGroup) {
 						// fmt.Printf("row : %s\n", row)
 
@@ -276,19 +275,19 @@ func GenesIngest(c echo.Context) error {
 							Chrom:      chromosomeClean,
 							Start:      start,
 							End:        end,
-							AssemblyId: _assId,
+							AssemblyId: _asmId,
 						}
 
 						iz.GeneIngestionBulkIndexingQueue <- &structs.GeneIngestionQueueStructure{
 							Gene:      discoveredGene,
 							WaitGroup: _gwg,
 						}
-					}(rowText, chromHeaderKey, startKey, endKey, nameHeaderKeys, geneNameHeaderKeys, _assId, &geneWg)
+					}(rowText, chromHeaderKey, startKey, endKey, nameHeaderKeys, geneNameHeaderKeys, _asmId, &geneWg)
 				}
 
 				geneWg.Wait()
 
-				fmt.Printf("%s ingestion done!\n", _assId)
+				fmt.Printf("%s ingestion done!\n", _asmId)
 				fmt.Printf("Deleting %s\n", unzippedFileName)
 				err = os.Remove(fmt.Sprintf("%s/%s", gtfPath, unzippedFileName))
 				if err != nil {
@@ -335,11 +334,7 @@ func GenesGetByNomenclatureWildcard(c echo.Context) error {
 	// Assembly ID
 	// perform wildcard search if empty/random parameter is passed
 	// - set to Unknown to trigger it
-	var assId constants.AssemblyId
-	if gc.AssemblyId != assemblyId.Unknown {
-		// retrieve passed parameter if is valid
-		assId = gc.AssemblyId
-	}
+	asmId := gc.AssemblyId
 
 	// Size
 	var (
@@ -354,10 +349,10 @@ func GenesGetByNomenclatureWildcard(c echo.Context) error {
 		}
 	}
 
-	fmt.Printf("Executing wildcard genes search for term %s, assemblyId %s (max size: %d)\n", term, assId, size)
+	fmt.Printf("Executing wildcard genes search for term %s, assemblyId %s (max size: %d)\n", term, asmId, size)
 
 	// Execute
-	docs, geneErr := esRepo.GetGeneDocumentsByTermWildcard(cfg, es, chromosomeSearchTerm, term, assId, size)
+	docs, geneErr := esRepo.GetGeneDocumentsByTermWildcard(cfg, es, chromosomeSearchTerm, term, asmId, size)
 	if geneErr != nil {
 		return c.JSON(http.StatusOK, map[string]interface{}{
 			"status":  500,

src/api/mvc/main.go

@@ -3,7 +3,6 @@ package mvc
 import (
 	"gohan/api/contexts"
 	"gohan/api/models/constants"
-	a "gohan/api/models/constants/assembly-id"
 	gq "gohan/api/models/constants/genotype-query"
 	"strings"
 
@@ -12,7 +11,7 @@ import (
 	"github.com/labstack/echo"
 )
 
-func RetrieveCommonElements(c echo.Context) (*elasticsearch.Client, string, int, int, string, string, []string, constants.GenotypeQuery, constants.AssemblyId, string) {
+func RetrieveCommonElements(c echo.Context) (*elasticsearch.Client, string, int, int, string, string, []string, constants.GenotypeQuery, string, string) {
 	gc := c.(*contexts.GohanContext)
 	es := gc.Es7Client
 
@@ -48,11 +47,7 @@ func RetrieveCommonElements(c echo.Context) (*elasticsearch.Client, string, int,
 		}
 	}
 
-	assemblyId := a.Unknown
-	assemblyIdQP := c.QueryParam("assemblyId")
-	if len(assemblyIdQP) > 0 && a.IsKnownAssemblyId(assemblyIdQP) {
-		assemblyId = a.CastToAssemblyId(assemblyIdQP)
-	}
+	assemblyId := c.QueryParam("assemblyId")
 
 	return es, chromosome, lowerBound, upperBound, reference, alternative, alleles, genotype, assemblyId, datasetString
 }

src/api/repositories/elasticsearch/genes.go

@@ -12,8 +12,6 @@ import (
 	"time"
 
 	"gohan/api/models"
-	"gohan/api/models/constants"
-	assemblyId "gohan/api/models/constants/assembly-id"
 	"gohan/api/utils"
 
 	"github.com/elastic/go-elasticsearch/v7"
@@ -106,7 +104,7 @@ func GetGeneBucketsByKeyword(cfg *models.Config, es *elasticsearch.Client) (map[
 }
 
 func GetGeneDocumentsByTermWildcard(cfg *models.Config, es *elasticsearch.Client,
-	chromosomeSearchTerm string, term string, assId constants.AssemblyId, size int) (map[string]interface{}, error) {
+	chromosomeSearchTerm string, term string, asmId string, size int) (map[string]interface{}, error) {
 
 	if cfg.Debug {
 		http.DefaultTransport.(*http.Transport).TLSClientConfig = &tls.Config{InsecureSkipVerify: true}
@@ -115,10 +113,10 @@ func GetGeneDocumentsByTermWildcard(cfg *models.Config, es *elasticsearch.Client
 	// Nomenclature Search Term
 	nomenclatureStringTerm := fmt.Sprintf("*%s*", term)
 
-	// Assembly Id Search Term (wildcard by default)
+	// Assembly ID Search Term (wildcard by default)
 	assemblyIdStringTerm := "*"
-	if assId != assemblyId.Unknown {
-		assemblyIdStringTerm = string(assId)
+	if asmId != "" {
+		assemblyIdStringTerm = asmId
 	}
 
 	var buf bytes.Buffer
@@ -217,7 +215,7 @@ func GetGeneDocumentsByTermWildcard(cfg *models.Config, es *elasticsearch.Client
 	return result, nil
 }
 
-func DeleteGenesByAssemblyId(cfg *models.Config, es *elasticsearch.Client, assId constants.AssemblyId) (map[string]interface{}, error) {
+func DeleteGenesByAssemblyId(cfg *models.Config, es *elasticsearch.Client, asmId string) (map[string]interface{}, error) {
 
 	if cfg.Debug {
 		http.DefaultTransport.(*http.Transport).TLSClientConfig = &tls.Config{InsecureSkipVerify: true}
@@ -227,7 +225,7 @@ func DeleteGenesByAssemblyId(cfg *models.Config, es *elasticsearch.Client, assId
 	query := map[string]interface{}{
 		"query": map[string]interface{}{
 			"match": map[string]interface{}{
-				"assemblyId": string(assId),
+				"assemblyId": asmId,
 			},
 		},
 	}

src/api/repositories/elasticsearch/variants.go

@@ -13,7 +13,6 @@ import (
 
 	"gohan/api/models"
 	c "gohan/api/models/constants"
-	a "gohan/api/models/constants/assembly-id"
 	gq "gohan/api/models/constants/genotype-query"
 	s "gohan/api/models/constants/sort"
 	z "gohan/api/models/constants/zygosity"
@@ -110,7 +109,7 @@ func GetDocumentsContainerVariantOrSampleIdInPositionRange(cfg *models.Config, e
 	reference string, alternative string, alleles []string,
 	size int, sortByPosition c.SortDirection,
 	includeInfoInResultSet bool,
-	genotype c.GenotypeQuery, assemblyId c.AssemblyId,
+	genotype c.GenotypeQuery, assemblyId string,
 	getSampleIdsOnly bool) (map[string]interface{}, error) {
 
 	// begin building the request body.
@@ -405,7 +404,7 @@ func CountDocumentsContainerVariantOrSampleIdInPositionRange(cfg *models.Config,
 	chromosome string, lowerBound int, upperBound int,
 	variantId string, sampleId string, datasetString string,
 	reference string, alternative string, alleles []string,
-	genotype c.GenotypeQuery, assemblyId c.AssemblyId) (map[string]interface{}, error) {
+	genotype c.GenotypeQuery, assemblyId string) (map[string]interface{}, error) {
 
 	// begin building the request body.
 	mustMap := []map[string]interface{}{{
@@ -465,7 +464,7 @@ func CountDocumentsContainerVariantOrSampleIdInPositionRange(cfg *models.Config,
 			}})
 	}
 
-	if assemblyId != "" && assemblyId != a.Unknown {
+	if assemblyId != "" {
 		mustMap = append(mustMap, map[string]interface{}{
 			"match": map[string]interface{}{
 				"assemblyId": map[string]interface{}{