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This is a BioDIGS in the Classroom companion guide for the BioDIGS project. This particular activity guides students through exploration of biosynthetic gene clusters in the BioDIGS samples using Galaxy

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BioDIGS: Biosynthetic Gene Clusters

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This course was created from the AnVIL Template, which is based on the OTTR Template

You can see the rendered course material here

About this course

This is a companion training guide for BioDIGS, a GDSCN project that brings a research experience into the classroom. In this module, students will explore microbiome data for the presence of biosynthesis genes. They will run analyses using antiSMASH as implemented on Galaxy. Visit the BioDIGS (BioDiversity and Informatics for Genomics Scholars) website here for more information about this collaborative, distributed research project, including how you can get involved!

The GDSCN (Genomics Data Science Community Network) is a consortium of educators who aim to create a world where researchers, educators, and students from diverse backgrounds are able to fully participate in genomic data science research. You can find more information about its mission and initiatives here.

Target Audience

The activity in this guide are written for undergraduate students and beginning graduate students.

Platform

The activities in this guide are demonstrated on NHGRI's AnVIL cloud computing platform. AnVIL is the preferred computing platform for the GDSCN. However, all of these activities can be done using the online Galaxy portal.

Data

The data generated by the BioDIGS project is available as an R package (BioDIGSData, https://github.com/fhdsl/BioDIGSData), through the BioDIGS website, or through an AnVIL workspace.

Data about the soil itself as well as soil metal content was generated by the Delaware Soil Testing Program at the University of Delaware. Sequences were generated by the Johns Hopkins University Genetic Resources Core Facility and by PacBio.

Encountering problems?

If you are encountering any problems with this course, please file a GitHub issue or contact Ava Hoffman (ahoffma2 at fredhutch.org) or Elizabeth Humphries (ehumphri at fredhutch.org).

Creative Commons License
All materials in this course are licensed under a Creative Commons Attribution 4.0 International License unless noted otherwise.

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This is a BioDIGS in the Classroom companion guide for the BioDIGS project. This particular activity guides students through exploration of biosynthetic gene clusters in the BioDIGS samples using Galaxy

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