iDISK

Homepage URL: https://conservancy.umn.edu/handle/11299/204783

Description: The Integrated Dietary Supplement Knowledge Base (iDISK) contains data on a variety of dietary supplements, including vitamins, herbs, minerals, etc. The data have been standardized and integrated from the Dietary Supplements Label Database (DSLD), the "About Herbs" database from Memorial Sloan Kettering Cancer Center (MSKCC), the Canadian Natural Health Products and Ingredients database (NHP), and the Natural Medicines Comprehensive Database (NMCD) developed by the Therapeutic Research Center (TRC). iDISK contains a variety of attributes and relationships describing information about each dietary supplement such as which products it is an ingredient of and what drugs it might interact with.

General Schema

iDISK contains 7 concept types and 6 relation types:

Concept Types

• SDSI: Semantic Dietary Supplement Ingredient
• DSP: Dietary Supplement Product
• DIS: Disease or Syndrome
• SPD: Pharmaceutical Drug
• SOC: System Organ Class
• SS: Sign or Symptom
• TC: Therapeutic Class

Following the UMLS, concepts are collections of synonymous atoms. An atom is a term (e.g. a possible name for a supplement, such as "Ginkgo" or "Ginkgo Biloba") from a given data source.

Relation types

• has_adverse_effect_on(SDSI, SOC)
• has_adverse_reaction(SDSI, SS)
• has_ingredient(DSP, SDSI)
• has_therapeutic_class(SDSI, TC)
• interacts_with(SDSI, SPD)
• is_effective_for(SDSI, DIS)

Additional links:

• 2020 paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075538/